@article{Memon_Tunio_Bano_Jatt_Maka_2020, title={Evaluation of Putative Association Between Celiac Disease and Helicobacter pylori Infection in Hyderabad, Sindh: Association Between Celiac Disease and Helicobactor pylori Infection}, volume={63}, url={https://v2.pjsir.org/index.php/biological-sciences/article/view/1497}, DOI={10.52763/PJSIR.BIOL.SCI.63.3.2020.157.162}, abstractNote={<p>Celiac disease is an autoimmune mediated enteropathy caused by ingestion of gluten and affects approximately 1% of the population. It has significant deleterious effects on health and mortality. <em>Helicobacter pylori </em>is the major causative agent of peptic ulcer and gastric cancer. The aim of this study was to assess the prevalence of both <em>H. pylori </em>(HP) and celiac disease (CD) as mono and co-infections and to find out the possible association between CD and presence of HP. A total of 172 blood samples from individuals suspected of CD and HP infection were collected during March to December, 2015 from Hyderabad. Serum analyzed for presence of anti-HP antibodies for evaluation of HP infection and tissue transglutaminase IgA antibodies (tTGA) for detection of CD. The serodiagnosis data revealed that out of 172 samples tested 19.19% were positive for CD which included 6.98% (n=12) male patients, whereas 12.21% (n=21) were females. The HP was detected in 44.77% (n=77) including 22.09% (n=38) males and 22.67% (n=39) females out of the 33 CD positive cases, HP was detected in 17 (9.88%). HP in CD positive cases was found to be 6.60% in males 9.43% in females respectively. The HP prevalence in non-CD patients appeared to be high such as 18.02% and 16.86%. In conclusion, the data of the present study indicates that HP is more prevalent than CD.</p> <p> </p>}, number={3}, journal={Biological Sciences - PJSIR}, author={Memon, Babar Aijaz and Tunio, Sarfraz Ali and Bano, Shaista and Jatt, Abdul Nabi and Maka, Ghulam Asghar}, year={2020}, month={Nov.}, pages={157–162} }