?HYPOTENSIVE ACTION OF AN EXTRACT OF HIBISCUS ROSA SINENSIS, LINN

Authors

  • Shahnaz Ahmed Pharmaceutical and Fine Chemical Research Centre, PCSIR Laboratories Complex, Karachi-75280, Pakistan
  • Shamim Qureshi Pharmaceutical and Fine Chemical Research Centre, PCSIR Laboratories Complex, Karachi-75280, Pakistan
  • Maryam Mirza Pharmaceutical and Fine Chemical Research Centre, PCSIR Laboratories Complex, Karachi-75280, Pakistan
  • Naseem M Qadri Pharmaceutical and Fine Chemical Research Centre, PCSIR Laboratories Complex, Karachi-75280, Pakistan
  • A Q S Bukhari Pharmaceutical and Fine Chemical Research Centre, PCSIR Laboratories Complex, Karachi-75280, Pakistan

Keywords:

Hibiscus rosa sinensis, Aqueous extract, Hypotensive action.

Abstract

Hypotensive action of extract of pink flowers of Hibiscus rosa sinensis, Linn. was investigated in rats and dogs: It was
foundthat45 mgkg' ofan aqueousextractofpinkflowers loweredthebloodpressureofratsfrom 80 mmHg to40 mmHg
while adose of60 mgkg ' of sameextract produceda fallinblood pressureofdogsfrom 120 mmHgto40 mmHg, butthe
duration of hypotensive action was more than 3-4 h in both thecases i.e. rats and dogs. Also the biphasic response of the
drug and its possible mode of action is discussed.

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Published

2001-06-18

How to Cite

Ahmed, S., Qureshi, S., Mirza, M., Qadri, N. M., & Bukhari, A. Q. S. (2001). ?HYPOTENSIVE ACTION OF AN EXTRACT OF HIBISCUS ROSA SINENSIS, LINN. Biological Sciences - PJSIR, 44(3), 168–170. Retrieved from http://v2.pjsir.org/index.php/biological-sciences/article/view/1905

Issue

Vol. 44 No. 3 (2001): Pakistan Journal of Scientific and Industrial Research

Section

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