?REAGENTS FOR NEW HETEROANNELATION REACTIONS: AZA REAGENTS

Authors

  • Shaifullah Chowdhury A Z M Department of Chemistry, University of Chittagong, Chittagong 4331, Bangladesh
  • Saidur Rahman M Department of Chemistry, University of Chittagong, Chittagong 4331, Bangladesh
  • Bhuiyan M M H Department of Chemistry, University of Chittagong, Chittagong 4331, Bangladesh
  • Yasmin L Department of Chemistry, University of Chittagong, Chittagong 4331, Bangladesh

Keywords:

Aza reagents, Heteroannelation, Hydrazides.

Abstract

Aza reagents were prepared from different hydrazides. Reactions of ortho-aminoesters and ortho-aminonitriles with aza
reagents have been studied in different solvents. Aza reagents with ortho-aminoesters and ortho-aminonitriles in presence
ofp-toluene sulphonic acid in dry CHJCN or acetic acid furnished the tricyclic derivatives N~[2-(methylthio)-4-oxo-5, 6,
7, 8-tetrahydro [I]benzothieno [2, 3-d]pyrimidine-3 (4H)-yl]carbamic acid ethyl ester (8), 5, 6, 7, 8-tetrahydro-2-methylthio-
4-oxo [I] benzothieno [2, 3-d]pyrimidin-3 (4H) acetamide (9) and 5, 6, 7, 8-tetrahydro-2-methylthio-4-oxo [I] benzothieno
[2, 3-d]pyrimidine-3 (4H)-benzamide (10), whereas, in pyridine medium these reactions afforded uncyclized urethane
products (11, 12 and 13). .

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Published

2000-06-26

How to Cite

A Z M, S. C., Rahman M, S., M M H, B., & L, Y. (2000). ?REAGENTS FOR NEW HETEROANNELATION REACTIONS: AZA REAGENTS. Biological Sciences - PJSIR, 43(4), 201–204. Retrieved from http://v2.pjsir.org/index.php/biological-sciences/article/view/2032

Issue

Vol. 43 No. 4 (2000): Pakistan Journal of Scientific and Industrial Research

Section

Articles