Selective Nitrations of 2-(1'-Phenylpyrazol-4'-yl) Benzimidazoles

Nitrations of Pyrazoles

Authors

  • Misbahul Ain Khan Department of Chemistry, Islamia University, Bahawalpur, Pakistan
  • Sabiha Rashid Department of Chemistry, Division of Science and Technology, University of Education, Lahore, Pakistan

Keywords:

pyrazoles, benzimidazoles, nitration, mass spectra

Abstract

Nitration of 2-(1'-phenylpyrazol-4'-yl) benzimidazole ring system was found to be temperature dependent. Room temperature nitration occurred at the phenyl ring of pyrazole, while at 100 °C, a dinitrated product is obtained where the second nitro group is introduced at the 5-position of the benzimidazole ring. Nitration at 100 °C leads directly to the expected dinitration product. Mass spectral fragmentations for both the compounds is described.

 

 

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Published

2009-12-28

How to Cite

Khan, M. A., & Rashid, S. (2009). Selective Nitrations of 2-(1’-Phenylpyrazol-4’-yl) Benzimidazoles: Nitrations of Pyrazoles. Biological Sciences - PJSIR, 52(6), 289–292. Retrieved from http://v2.pjsir.org/index.php/biological-sciences/article/view/568

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