EFFECT OF AQUEOUS EXTRACT OF AVICINNIA MARINA ON MYOCARDIAL CONTRAC- TION OF ISOLATED MAMMALIAN HEART

Authors

  • Shahnaz Ahmed Pharmaceutical Research Center, Pharmacology Section, PCSIR Laboratories Complex, Karachi-75280, Pakistan
  • Atiq-ur- Rahman Pharmaceutical Research Center, Pharmacology Section, PCSIR Laboratories Complex, Karachi-75280, Pakistan

Keywords:

: Avicinnia marina, Mangrove, Mammalian heart.

Abstract

Aqueous extract of Avicinnia marina commonly known as mangrove showed a marked inhibitory action on isolated mammalian heart in-vitro. The degree of inhibition was found to be highly dose dependent. A dose of 100 mg/kg caused cardiac arrest for few seconds. The force and magnitude of cardiac contractions were regained to pre-injection level after 1.6-2 min. Pretreatment with atropine was found to have no effect on myocardial contractions. The amplitude of cardiac contractions was reduced slightly after the administration of adrenaline.

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Published

2004-10-25

How to Cite

Ahmed, S., & Rahman, A.- ur-. (2004). EFFECT OF AQUEOUS EXTRACT OF AVICINNIA MARINA ON MYOCARDIAL CONTRAC- TION OF ISOLATED MAMMALIAN HEART. Biological Sciences - PJSIR, 47(5), 390–393. Retrieved from http://v2.pjsir.org/index.php/biological-sciences/article/view/1557

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