SYNTHESIS OF 5 H-IMIDAZO [1, 2-a] THIOPYRAN0-[4', 3': 4, 5] THIEN0[2, 3-d] PYRIM1DIN-5-0NE

Authors

  • A Z M Shaifullah Chowdhur y Department of Chemistry,Chittagong University, Chittagong-4331,Bangladesh
  • M M Rahman Khandker Department of Chemistry,Chittagong University, Chittagong-4331,Bangladesh
  • M M H Bhuiyan Department of Chemistry,Chittagong University, Chittagong-4331,Bangladesh
  • M K Hossain Department of Chemistry,Chittagong University, Chittagong-4331,Bangladesh

Keywords:

Tetrahydrothiopyran, Annelating reagent, Fused pyrimidines

Abstract

The enamino-ester, ethyl, 2-amino-4,7-dihydro-5H-thieno[2,3-c]thiopyrano-3-carboxylate (5) was prepared from tetrahydrothiopyran-4-one (4). Annelating reagent, 5-methyl-2-methylthioimidazoline (8) was prepared starting from J , 2-diaminopropane (6) via 5-methyl-2-imidazolidinethione (7). The reaction of enamino-ester (5) with the annelating reagent (8) i n HMPTA leaded to new 1, 2, 3, 6, 7, 9-hexahydro-5H-imidazo[ I , 2-a]thiopyrano[4', 3':4, 5]thieno-[2, 3- d]pyrimidin-5-one (9) in good yield.

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Published

2001-04-23

How to Cite

Chowdhur, A. Z. M. S., Khandker, M. M. R., Bhuiyan, M. M. H., & Hossain, M. K. (2001). SYNTHESIS OF 5 H-IMIDAZO [1, 2-a] THIOPYRAN0-[4’, 3’: 4, 5] THIEN0[2, 3-d] PYRIM1DIN-5-0NE. Biological Sciences - PJSIR, 44(2), 63–66. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/1877

Issue

Vol. 44 No. 2 (2001): Pakistan Journal of Scientific and Industrial Research

Section

Articles