Antioxidant Activities and Phenolic Profile of Senna alexandrina

Phenolic Profile of Senna alexandrina

Authors

  • Syed Mubashar Sabir Department of Chemistry, University of Poonch, Rawalakot, Azad Kashmir, Pakistan
  • Maria Khalid Department of Chemistry, University of Poonch, Rawalakot, Azad Kashmir, Pakistan
  • Muhammad Usman Hameed Department of Chemistry, University of Poonch, Rawalakot, Azad Kashmir, Pakistan
  • Muhammad Zubair Khan Department of Plant Breeding and Molecular Genetics, University of Poonch, Rawalakot, Azad Kashmir, Pakistan

Keywords:

Senna alexandrina, DPPH activity, lipid peroxidation, HPLC analysis, metal chelation activity

Abstract

The purpose of the present study was to evaluate and compare the antioxidant activities of Senna alexandrina leaves as well to determine its phenolic profile. The antioxidant activity was analyzed by in vitro lipid peroxidation assay, DPPH radical scavenging activity, ABTS assay, antioxidant potential assay and metal chelation assay. The extract showed remarkable scavenging activities (58% in DPPH and 68% in ABTS assay respectively), iron chelation (60%), reduction potential (68%). The extract reduced the lipid peroxidation against FeSO4 (60%) and sodium nitroprusside (50%) in phospholipid homogenate extracted from egg yolk. HPLC analysis revealed the presence of quercetin, pyrogallol and gallic acid in leaves extract. On the basis of these results it is concluded that leaves extract of S. alexandrina are rich source of antioxidants and contain important phytochemicals.

 

 

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Published

2025-10-24

How to Cite

Syed Mubashar Sabir, Maria Khalid, Muhammad Usman Hameed, & Muhammad Zubair Khan. (2025). Antioxidant Activities and Phenolic Profile of Senna alexandrina: Phenolic Profile of Senna alexandrina. Biological Sciences - PJSIR, 68(3), 328–334. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/3157

Issue

Vol. 68 No. 3 (2025): Pakistan Journal of Scientific and Industrial Research Series B: Biological Sciences

Section

Articles