Antimicrobial Screening of Some Derivatives of Methyl ?-D-Glucopyranoside

Antimicrobial Studies of Methyl Gloucopyranoside Derivatives

Authors

  • Abul K. M. S. Kabir Department of Chemistry, University of Chittagong, Chittagong-433, Bangladesh
  • Sarkar M. A. Kawsar Department of Chemistry, University of Chittagong, Chittagong-433, Bangladesh
  • Mohammad M. R. Bhuiyan Department of Chemistry, University of Chittagong, Chittagong-433, Bangladesh
  • Md. Safiqur Rahman Department of Microbiology, University of Chittagong, Chittagong-433, Bangladesh
  • Mohammad E. Chowdhury Department of Chemistry, University of Chittagong, Chittagong-433, Bangladesh

Keywords:

antibacterial activities, antifungal activities, methyl glucopyranoside derivatives

Abstract

In vitro antimicrobial functionality test of methyl 4,6-O-cyclohexylidene-a-D-glucopyranoside and its twelve acylated derivatives against ten human pathogenic bacteria and six phytopathogenic fungi comparative to Ampicillin and Nystatin revealed the tested chemicals to possess moderate to good antibacterial and antifungal activity and to be more effective against fungal phytopathogens. Many of these chemicals exhibited better antimicrobial activity than the standard antibiotics. Minimum Inhibition Concentration (MIC) of methyl 4,6-O-cyclohexylidene-2-O-myristoyl- 3-O-palmitoyl-a-D-glucopyranoside against Bacillus cereus, Bacillus subtilis and Staphylococcus aureus was 25, 12.5 and 25 ?g/disc, respectively.

 

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Published

2009-06-29

How to Cite

Kabir, A. K. M. S., Kawsar, S. M. A., Bhuiyan, M. M. R., Rahman, M. S., & Chowdhury, M. E. (2009). Antimicrobial Screening of Some Derivatives of Methyl ?-D-Glucopyranoside: Antimicrobial Studies of Methyl Gloucopyranoside Derivatives. Biological Sciences - PJSIR, 52(3), 138–142. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/536