SPECTROPHOTOMETRIC METHOD OF THE DETERMINATION OF GOLD (III) BY USING IMIPRAMINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE
Keywords:
Imipramine hydrochloride, Promethazine hydrochloride, Gold(III) halides complexes.Abstract
Imipramine hydrochloride [IPM·HCl] and promethazine hydrochloride [PMT·HCl] were used for the spectrophotometric
determination of gold (III) in the aqueous solution. The halides complexes of gold (III) created a coloured coupling
with the studied drugs which were extractable in chloroform. These new compounds were characterised by IR, UV-VIS
spectra and thermal and elemental analysis. Rapid and sensitive spectrophotometric method for the determination of
gold (III) in the aqueous solution is described. The absorbance was found to be linear function of the gold (III)
concentration in the range from 0.2 to 20 x 10-1 mg. The ratio of complex [AuX4]- to the organic cation from drug in the
obtained compounds was determined as 1:1. The method was satisfactorily applied to the analysis of gold (III). A great
advantage of the proposed method is that the trace amounts of gold (III) can also be examined.
