MAMMALIAN TOXICITY STUDIES OF NIMBOKIL-60 EC

Authors

  • SA R Kazmi Tropical Agricultural Research Centre, PAR C, Karachi, Pakistan
  • N M Qadri PCSIR Laboratories Complex, Karachi-75280, Pakistan Tropical Agricultural Research Centre, PAR C, Karachi, Pakistan
  • Y Badar PCSIR Laboratories Complex, Karachi-75280, Pakistan

Keywords:

Neem, Nimbokil, Toxicology, Phytochemicals, Botanical pesticides.

Abstract

Nimbokil-60 EC, an expelled neem (Azadirachta indica A. Juss) seed oil based insecticide was tested to determine its
mammalian toxicity. Tests for acute and percentaneous toxicity, acute inhalation, skin and eye irritation, sub-chronic
effects and effect on fertility were carried out. Results revealed that 'Nimbokil' had no adverse or ill effects on the test
animals under administered doses. LD-50 was found to be 16 ml kg" body-weight of the animals. Autopsy observation
showed no gross changes in vital organs i.e. heart, lungs, liver, ovary and testicles of the test animals. When applied as
such (100% concentration) completely within 72 h. However, at lower concentrations, no eye irritation was noticed. It
is therefore, concluded that Nimbokil-60EC be classified as non-toxic'.

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Published

2001-08-20

How to Cite

Kazmi, S. R., Qadri, N. M., & Badar, Y. (2001). MAMMALIAN TOXICITY STUDIES OF NIMBOKIL-60 EC. Biological Sciences - PJSIR, 44(4), 234–238. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/1933

Issue

Vol. 44 No. 4 (2001): Pakistan Journal of Scientific and Industrial Research

Section

Articles