?POTENTIAL ANTIBACTERIAL AGENTS PART-IV. SYNTHESIS OF NEW 1[2-PYRIMIDINO ]_. AMINO-METHYL BENZIMIDAZOLES AND 1,2,. 3 BENZOTRIAZOLES
Keywords:
Antibacterial activity, Mannich bases, Hydroxybenzimidazole.Abstract
Condensation reaction of (IS)-2(a-hydroxy ethyl) benzimidazole (I), 2-hydroxymethyl benzimidazole (II) and 1,2,3
benzotriazole (III) with pyrimidine viz: 2-aminopyrimidine (IV-a) and4, 6-dimethyl-pyrimidine (IV-b) under thecondi-
tion of Mannich reaction afforded the hitherto unreported substituted l-arninomethyl (hydroxyalkyl) benzimidazoles and
l-aminomethyl benzotriazoles which were assigned the structures (Va-d) and (VIa-b) on the basis of their lR, IH-NMR
and HREIMS spectral studies. Antibacterial activity was also evaluated.
Published
1998-04-20
How to Cite
Hussainv, S. A., Sarfaraz, T. B., Murtaza, N., & Faiai, S. (1998). ?POTENTIAL ANTIBACTERIAL AGENTS PART-IV. SYNTHESIS OF NEW 1[2-PYRIMIDINO ]_. AMINO-METHYL BENZIMIDAZOLES AND 1,2,. 3 BENZOTRIAZOLES. Biological Sciences - PJSIR, 41(2), 63–67. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/2233
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