?SYNTHESIS OF SOME HYDRAZONE ANDPYRAZOLINE DERIVATIVES

Authors

  • HASSANM. FAIDALLAH Department of Chemistry, Faculty of Science, University of Alexandria, Alexandria, Egypt
  • HASSANM MOKHTAR Department of Chemistry, Faculty of Science, University of Alexandria, Alexandria, Egypt
  • AHMED NASSAR Department of Chemistry, Faculty of Science, University of Alexandria, Alexandria, Egypt
  • MOHAMEDM AHMED Department of Chemistry, Faculty of Science, University of Alexandria, Alexandria, Egypt

Keywords:

Hydrazones, Pyrazolines, Preparation.

Abstract

Condensation of chalcones (I) with aroyl-and arylhydrazines afforded the corresponding hydrazones (2 and 3),
cyclization of the hydrazones (3) with HCI gave the pyrazoline derivatives (4) which on oxidation with bromine water
yielded the corresponding pyrazoles (5). Addition of 5-p-bromophenyl-3-methyl-l-p-sulphamylphcnylpyrazole (5c)
to allylisothiocyanate afforded the thiourea derivative (6) which was readily cyclized with ethyl bromoacctatc to the
corresponding oxothiazolidine (7).

Published

1995-06-19

How to Cite

FAIDALLAH, H., MOKHTAR, H., NASSAR, A., & AHMED, M. (1995). ?SYNTHESIS OF SOME HYDRAZONE ANDPYRAZOLINE DERIVATIVES. Biological Sciences - PJSIR, 38(5-6), 179–181. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/2468

Issue

Vol. 38 No. 5-6 (1995): Pakistan Journal of Scientific and Industrial Research

Section

Articles