SYNTHESIS OF NITROGEN-OXYGEN HETEROCYCLES FROM CARBOHYDRATE PRECURSOR

Authors

  • M. ARDEL RAHMAN Chemistry Department, Faculty of Science,Alexandria University, Alexandria, Egypt
  • M. EL SADEK Chemistry Department, Faculty of Science,Alexandria University, Alexandria, Egypt
  • S. ABDEL BAKY Chemistry Department, Faculty of Science,Alexandria University, Alexandria, Egypt
  • N. EL SOCCARY Chemistry Department, Faculty of Science,Alexandria University, Alexandria, Egypt

Keywords:

Tetrahydroindole, Benzoylhydrazone, Oxadiazole.

Abstract

6, 6-Dimethyl-4-oxo-4, 5, 6, 7-tetrahydroindol-2-carboxaldehyde (2) condensed with benzoylhydrazine to afford
the corresponding benzoyl hydrazone derivative '3'. Oxidative cycJization of3 gave the corresponding 1,3, 4-oxadiaz<;>lemercuric
complex '4'. On the other hand, the methylated aldehyde '5' condensed with a number of aryl and acylhydrazines
to afford the corresponding hydrazones '6-18'. Oxidative cycJization of the acylhydrazones gave the corresponding
1,3, 4-oxadiazoles '19-27'. The structures were confirmed by rR, 1H-NMR and mass spectra.

Published

2022-06-09

How to Cite

RAHMAN, M. A. ., SADEK, . M. E. ., BAKY , . S. A., & SOCCARY, . . N. E. . (2022). SYNTHESIS OF NITROGEN-OXYGEN HETEROCYCLES FROM CARBOHYDRATE PRECURSOR. Biological Sciences - PJSIR, 37(8), 309–312. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/2699

Issue

Vol. 37 No. 8 (1994): Pakistan Journal of Scientific and Industrial Research

Section

Articles