PRODUCTION OF OXYTETRACYCLINE BY DIFFERENT MUTANTS OF STREPTOMYCES RIMOSUS INDUCED BY DRY AND WET HEAT IN A DATE MEDIUM

Authors

  • N.A BAESHIN Biology Biochemistry, Chemistry Departments, King Abduiazi University, Jeddah-21413, Saudi Arabia
  • A A ABou- ZEID Biology Biochemistry, Chemistry Departments, King Abduiazi University, Jeddah-21413, Saudi Arabia
  • A O. BAGHLAF Biology Biochemistry, Chemistry Departments, King Abduiazi University, Jeddah-21413, Saudi Arabia

Keywords:

Oxytetracycline, Mutants of S. rimosus, Dry and wet heat, Date medium.

Abstract

Dry heat was more effective as physical mutagen than wet heat for Streptomyces rimosus. The optimal dose oftemperature
for inducing auxotrophic mutants in Streptomyces rimosus was 55° under dry treatment conditions. Two
mutants only out of 138 dry and wet heat mutants produced higher antibiotic titres than the parent organism.

Published

2022-06-09

How to Cite

BAESHIN , N. ., ZEID , . . A. A. A.-., & BAGHLAF, . . A. O. . (2022). PRODUCTION OF OXYTETRACYCLINE BY DIFFERENT MUTANTS OF STREPTOMYCES RIMOSUS INDUCED BY DRY AND WET HEAT IN A DATE MEDIUM. Biological Sciences - PJSIR, 37(9), 388–391. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/2723