Quantization of Buspirone Hydrochloride in Pure and Pharmaceutical Formulations by Spectrophotometric Method

Quantization of Buspirone HCl

Authors

  • Asrar A. Kazi Applied Chemistry Research Centre, PCSIR Laboratories Complex, Ferozepur Road, Lahore-54600, Pakistan
  • Amina Mumtaz Applied Chemistry Research Centre, PCSIR Laboratories Complex, Ferozepur Road, Lahore-54600, Pakistan
  • Mohammad Usman Sabri Applied Chemistry Research Centre, PCSIR Laboratories Complex, Ferozepur Road, Lahore-54600, Pakistan
  • Mir Anjum Javed Government College of Science, Wahdat Road, Lahore, Pakistan

Keywords:

buspirone hydrochloride, ammonium molybdate, spectrophotometry.

Abstract

A simple and sensitive method is described for the determination of buspirone hydrochloride in bulk drug and in formulations employing spectrophotometric technique. The method is based on the interaction of buspirone hydrochloride with ammonium molybdate in acidic media and the absorbance is measured at 700 nm. Beer’s Law is obeyed in the range of 5 mg to 350 mg/ml and RSD is 0.96 % for buspirone hydrochloride. Analytical data for the determination of pure compound is presented along with the application of the proposed method for the analysis of pharmaceutical formulation.

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Published

2008-04-22

How to Cite

Kazi, A. A., Mumtaz, A., Sabri, M. U., & Javed, M. A. (2008). Quantization of Buspirone Hydrochloride in Pure and Pharmaceutical Formulations by Spectrophotometric Method: Quantization of Buspirone HCl. Biological Sciences - PJSIR, 51(2), 72–76. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/634

Issue

Vol. 51 No. 2 (2008): Pakistan Journal of Scientific and Industrial Research

Section

Articles