Synthesis and Biological Activity of 7-Benzyloxy and 7-Methoxy Flavone

Authors

  • Sayed Alam * •Department of Life Science and Biotechnology, Shirnane University, Matsue, Shimane 690-8504, Japan bDepartment of Chemistry, Rajshahi University ofEngineering and Technology, Rajshahi-6204 , Bangladesh
  • M. A. Jalil Miah Department of Chemistry, University of Rajshahi, Rajshahi-6204 , Bangladesh
  • Azizul Islam Department of Chemistry, University of Rajshahi, Rajshahi-6204 , Bangladesh

Keywords:

:. 7-h yd rox yfl avone, deri vati ves, antibacteri al an d an ti fu n gal acti v i ty

Abstract

. Benzyl and methyl d erivatives of 7-hydroxyflavone were synth esized from 2-hyd roxy-4 -benzyloxy­ acetophenon e and 2-hydroxy -4-methoxyacetophenone, respectivel y, via chal cone precu rsor and by the treatment with DMS0/ 12 , diphenyl sul ph ide and d ichloro d icyan o qu i n on e (DDQ). The an t i bacteri al and antifunga l activ i ty

of these flavones and thei r  correspond i ng chalcones were  fou nd  in  vitro by the  fi l ter  paper d i sc diffu si on method

and poi son ed food techn iq ue .

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Published

2007-04-25

How to Cite

Alam, S., Jalil Miah, M. A., & Islam, A. (2007). Synthesis and Biological Activity of 7-Benzyloxy and 7-Methoxy Flavone. Biological Sciences - PJSIR, 50(2), 80–84. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/761