ISOLATION AND PHARMACOLOGICAL SCREENING OF 8-O-ACETYL HARPAGIDE FROM AJUGA BRACTEOSA WALL

Authors

  • Nusrat Shafi Medicinal Botanic Centre, PCSIR Laboratories Peshawar, Peshawar-25120, Pakistan
  • Gull Akhtar Khan Medicinal Botanic Centre, PCSIR Laboratories Peshawar, Peshawar-25120, Pakistan
  • M Arfan Department of Chemistry, University of Peshawar, Peshawar, Pakistan
  • Kamal-ud-Din Ahmad Medicinal Botanic Centre, PCSIR Laboratories Peshawar, Peshawar-25120, Pakistan
  • N D Gilani Medicinal Botanic Centre, PCSIR Laboratories Peshawar, Peshawar-25120, Pakistan

Abstract

8-O-Acetyl harpagide was isolated and characterized from Ajuga bracteosa Wall, a species indigenous to Pakistan. Pharmacological screening of the compound for antibacterial, antifungal, antispasmodic, cardiotonic and antipyretic activities was carried out. The compound was found effective against a number of human pathogenic bacteria and fungi. Antispasmodic and cardiotonic effects elicited by the compound were also found. The compound also exhibited antipyretic activity when administered in the higher doses.

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Published

2004-06-28

How to Cite

Shafi, N., Khan, G. A., Arfan, M., Ahmad, K.- ud-D., & Gilani, N. D. (2004). ISOLATION AND PHARMACOLOGICAL SCREENING OF 8-O-ACETYL HARPAGIDE FROM AJUGA BRACTEOSA WALL. Biological Sciences - PJSIR, 47(3), 176–179. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/1504

Issue

Vol. 47 No. 3 (2004): Pakistan Journal of Scientific and Industrial Research

Section

Articles