SYNTHESIS OF 2, 3-DI (QUINOL-8-YL) 6-METHYLQUINOXALINE

Short Communication

Abstract

Quninoxalines are considered to have significant biological activity. Their reactions as well as their pharmacological actions continue to stimulate many investigations. Thus 2-methyl quinoxalines N ,N-dioxides substituted in the 3-position (e.g., with amide, amidino, hydrazinocarbonyl and ester groups) are potent bacteriocides (Cheeseman 1963; Cheeseman and Werstiuk 1978). Antibiotics of the triostin and quinomycin series, isolated from the cultures of Strep­ tomyces aureus, have been shown by degradative study to contain a quinoxaline-2-carbo xylic acid residue.