• MICROBIAL CONTAMINATION OF PHARMACEUTICAL PRODUCTS IN A TROPICAL ENVIRONMENT

Authors

  • I F Obuekwe Department of Pharmaceutical Microbiology, University of Benin, Benin-City, Nigeria
  • A O Ogbimi Department of Microbiology, University of Benin, Benin-City, Nigeria
  • C O Obuekwe Department of Biological Sciences, Faculty of Science, Kuwait University, PO Box 5969, Safat 13060, Kuwait

Keywords:

Tablets, Microbial contamination , Pharmaceuticals

Abstract

Tablets, both coated and non-coated were examined for the microbiological contamination, growth  and  survival. Bacteria  such as KlebsieUa aerogenes, Bacillus cereus, Pseudomonas  aeruginosa,  and  Staphylococcus  aureus  were  dominated  in all the samples screened. Fungi isolated were Penicillium chrysogenum, Aspergillus jlavus and some yeasts as Candida albicans and Saccharomyces spp. Total bacterial counts ranged from 2.0 x 103 to 8 x 107 colony forming units (CFU) per millilitre while mould units ranged from O .2 x  102 to  1.4 x  102  cfu/ml. The bacterial  isolates were further found  to be able to grow and  utilize  the drugs (tablets)  as  sole carbon  and  energy  sources.

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Published

2002-10-28

How to Cite

Obuekwe, I. F., Ogbimi, A. . O., & Obuekwe, C. O. (2002). • MICROBIAL CONTAMINATION OF PHARMACEUTICAL PRODUCTS IN A TROPICAL ENVIRONMENT. Biological Sciences - PJSIR, 45(5), 341–344. Retrieved from https://v2.pjsir.org/index.php/biological-sciences/article/view/1833

Issue

Vol. 45 No. 5 (2002): Pakistan Journal of Scientific and Industrial Research

Section

Articles